After breaking an almost year-long win drought, the Titans travel to NSW to meet a Rabbitohs team also sitting on a 1-3 record.
While the Gold Coast celebrated their success over the Wests Tigers in round four, South Sydney slipped to a third consecutive defeat when the Storm proved too good.
Wayne Bennett's troops were competitive for the majority of that contest but mistakes cruelled them. They'll be out to reassert themselves as competition heavyweights, though the Titans are hopeful of continuing to climb.
Rabbitohs: Wayne Bennett said on Friday that James Roberts would not be making his comeback, meaning Braidon Burns has earned a reprieve in the centres. Cody Walker returns from suspension with rookie Troy Dargan dropping out of the 17. Patrick Mago and Bayley Sironen replace Mark Nicholls and Keaon Koloamatangi on the interchange. Nicholls and Koloamatangi dropped out of the 19-man squad an hour before kick-off and Bryson Goodwin was the other player cut from the squad when it was reduced to 19 on Friday.
The Rabbitohs have won nine of their past 11 games against the Titans.
Titans: The Titans are 1-17, as named on Tuesday. Jai Whitbread and Tyrone Roberts dropped out of the playing squad on game day and Jarrod Wallace and Beau Fermor were omitted from the squad 24 hours before kick-off. The Titans have not defeated the Rabbitohs in Sydney since 2014.
Jai Arrow was enormous at lock in the Gold Coast's pressure-relieving win, frequently bending the line and popping smart offloads. He'll want to continue that form against the club he will join in 2021. Opposite him in the middle will be Cameron Murray, who is a different style of player but equally as impactful.