Rabbitohs Skipper and Kangaroos Centre Greg Inglis has been rested by Kangaroos Coach Mal Meninga ahead of their opening clash with Scotland. Meninga has also rested Johnathan Thurston, likely opting to unleash both stars against New Zealand in Round Two.

Kangaroos Coach Mal Meninga has named five debutants for the opening Four Nations match against Scotland, at Hull's KC Lightstream Stadium on Friday.

Fullback Matt Moylan (Kangaroo No 812), centre Justin O'Neill (813), five-eighth James Maloney (811), lock Jake Trbojevic (814) and interchange player Jake Friend (815) will all play in the green and gold jersey for the first time.

Cooper Cronk will play his 30th Test match for Australia against the Bravehearts.

"I always planned to ensure the entire 24-man squad has played across the Perth Test and the Four Nations match against Scotland and that will set us up nicely for the rest of the tournament," Kangaroos Coach Mal Meninga said.

"I do have an idea of what my best possible squad would be but all players know they can break into the top team with a strong performance."